I know that when a system is in its lowest level of energy, it is most stable. However, what if system 1 has lower energy than system 2, does it keep meaning so? Or do we need to examine their binding energies of them? If the systems have only two bodies, easy: the one which has lower binding energy is stabler because their bodies don't need so much energy to combine them ($E_{binding}=E_{total}-E_A-E_B$). But what about many-body systems? If the binding is only meaningful in the context of two, then what is the subtraction $E_{total}-E_A-\sum_i{E_i}$?
By saying "more stable", I mean that it is "easier to combine", not "more energetic".