Look at Faraday's law $$\oint \vec E\cdot \vec {dl} = - \frac d{dt}\int \vec B.\vec {dA}$$
We use the right Hand Rule to get the correct directions of the path and surface $\vec E$ and $\vec B$ are integrated over respectively.
Now suppose $\vec B$ points into the screen and increases over time. Using the Right Hand Rule, we integrate $\vec E$ around the path clockwise to to get an induced emf of V volts, say. If there was no minus sign in Faraday's Law, this would imply the induced current would be driven around the loop in a clockwise direction, and the direction of its changing magnetic field would add to the original changing magnetic field, producing a postive feedback effect and the creation of energy from nothing.
So the minus sign ensures the induced emf works against the change causing it, summarized in Lenz's law, and that energy is conserved.