Let $G$ be a group, represented on the C*-algebra of quantum observables. By Haag's theorem, if in the C*-algebra of quantum observables there are two $G$-invariant states that are also $G$-abelian (an asymptotic condition that it would be too long to explain here), then they are either equal or disjoint (the latter meaning that one cannot be written as a trace class operator in the GNS-representation of the other).
Therefore, since the Wightman axioms are set in a given representation of the algebra of observables, only one ground state (i.e. Poincaré- invariant and abelian state) can exist as a trace class operator. There may be however more than one $G$-invariant state, provided only one is $G$-abelian. I think that an example would be given by the free vacuum and the free Gibbs state of a scalar theory: they are both trace class in the Fock representation, and invariant (at least w.r.t. time translations).