In Reed & Simon's Methods of Mathematical Physics Volume II, they define a (Hermitian scalar) quantum field theory to be the quadruple $\langle \mathcal{H}, U, \varphi, D\rangle$ that satisfies the Wightman axioms. Here $\mathcal{H}$ is a separable Hilbert space, $U$ is a strongly continuous unitary representation of $\mathcal{H}$ of the restricted Poincare group, $D \subset \mathcal{H}$ is dense, and $\varphi: \mathscr{S}(\mathbb{R}^4) \rightarrow T(\mathcal{H})$ where $\mathscr{S}$ is the Schwartz space and $T(\mathcal{H})$ is the set of all (unbounded) operators on $\mathcal{H}$.
They define the Wightman functions as the operator valued distributions $\{\mathcal{W}_n\}$ where $$\mathcal{W}_n (f_1, \ldots, f_n) = \big(\psi_0, \varphi(f_1), \cdots \varphi(f_n)\psi_0\big)$$ and $\psi_0$ is the vacuum state in $\mathcal{H}$.
From what I have read, Schwinger functions $\{\mathcal{S}_n\}$ are defined are just the analytic continuation of $\{\mathcal{W}_n\}$ to imaginary time. Most resources present both sets of distributions as functions on $\mathbb{R}^4$ so the Wick rotation is easy to visualize, but this is less obvious when the domain is a function space and not space-time.
Based on the definition given by Reed and Simon it seems we are often given $\varphi$ so $\{\mathcal{W}_n\}$ is easily defined. When I first started studying axiomatic QFT my impression was that the axioms are used to construct the quantum field $\varphi$ from scratch. However, looking at these axioms, my impression now is that one instead constructs $\varphi$ using traditional means (for example, from a Lagrangian), and then checks if all the axioms are satisfied.
My questions can be summarized as follows:
Given that both $\mathcal{W}_n$ and $\mathcal{S}_n$ are distributions, how does one Wick rotate between them?
In reference to the last paragraph above, how does this work in practice? Where does $\varphi$ come from?
Lastly, is there some sort of uniqueness result for the Wightman functions? That is, if I have two sets of Wightman functions $\{\mathcal{W}_n\}$ and $\{\tilde{\mathcal{W}}_n\}$, do they correspond to the same scalar field (up to unitary equivalence)? And thus does are Wightman functions only applicable to scalar fields?