I) Yes, they are probably referring to that a Grassmann-odd operator needs not (super)commute with itself. Take e.g. the 1st order Grassmann-odd differential operator
$$\tag{1} D~:=~\frac{d}{d\theta}+ \theta\frac{d}{dt}. $$
In eq. (1) $t$ is a Grassmann-even variable and $\theta$ is a Grassmann-odd variable, which (super)commute
$$\tag{2} [t,t]_{SC}~=~0, \qquad [t,\theta]_{SC}~=~0, \qquad [\theta,\theta]_{SC}~=~2\theta^2~=~0.$$
In eq. (2) the bracket $[\cdot,\cdot]_{SC}$ denotes the super-commutator
$$\tag{3} [A,B]_{SC}~:=~ AB-(-1)^{|A|~|B|}BA. $$
The supercommutator is the appropriate$^1$ generalization of the notion of a commutator to superalgebras.
The super-commutator of $D$ operator (1) with itself is not zero:
$$\tag{4} [D,D]_{SC}~=~ 2D^2~=~2\frac{d}{dt}\neq 0 .$$
II) More generally, the fact that a Grassmann-odd operator (super)commute with itself is a non-trivial condition, which encodes non-trivial information about the theory. This is e.g. used in supersymmetry and in BRST formulations.
On the other hand, the super-commutator of an arbitrary Grassmann-even operator with itself is automatically zero.
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$^1$ One may wonder why one uses the supercommutator $[\cdot,\cdot]_{SC}$ rather than the ordinary commutator
$$\tag{5} [A,B]_{C}~:=~ AB-BA $$
in superalgebras? The commutator (5) satisfies a Jacobi identity, and the supercommutator (3) satisfies a super Jacobi identity, so that's a tie. :)
One physical motivation comes from canonical quantization: As is well-known, quantum mechanically, two Grassmann-graded operators may fail to commute or fail to supercommute. However classically ($\equiv$ when Planck's constant $\hbar$ is zero), for two Grassmann-graded functions $f$ and $g$, one would like that the appropriate bracket generalization $[f,g]$ vanishes. To ensure this one has to use the supercommutator $[\cdot,\cdot]_{SC}$ rather than the commutator $[\cdot,\cdot]_{C}$. From this perspective, the canonical anticommutator relation (CAR) for fermions is merely a quite natural quantum deformation of a classical supercommuting description. Moreover, the supercommutator (3) [as opposed to the commutator (5)] provides a unified description of CCR for bosons and CAR for fermions. See also e.g. this Phys.SE post and links therein.