It's widely known that, using famous equation $E=mc^2$, we can estimate energy in nuclear reactions, matter-antimatter reactions (the most powerful in the universe), etc.
It's also known that, in the case of nuclear reactions, a greatsmall portion of matter is converted into energy.
My question is: In a matter-antimatter reactions, absolutely ALL matter (100%) is converted into Energy? If not, how much % is? 99.9999...%?