There is a variety of silicon pixels being used in very high energy particle applications. I would like to know, if I have a detector with silicon pixels of dimensions N x M, how can I calculate what is the maximum spatial resolution I can obtain in every of these directions

There is a variety of silicon pixels being used in very high energy particle applications. I would like to know, if I have a detector with silicon pixels of dimensions $N \times M$, how can I calculate what is the maximum spatial resolution I can obtain in every of these directions