I'm reading about the tetrad formalism in GR and one main difference between the coordinate and the tetrad frame is that coordinate derivatives commute $\partial_\mu \partial_\nu = \partial_\nu \partial_\mu$, while tetrad derivatives do not $\partial_m \partial_n \neq \partial_n \partial_m$.
Considering that partial derivatives are variations along a direction and tetrads are simply an orthonormal frame, what is the physical interpretation of the non-commutativity of tetrad directional derivatives?