In general it seems quite unlikely, unless there is some special symmetry that enforces this. I guess it could also sometimes happen in 0+1 dimensions because here the space of fields is much nicer.
But anyway, the closest example that I can think of is $\mathcal N=2$ supersymmetry in four dimensions. Here, due to supersymmetry, the effective action is one-loop exact, and the only corrections are non-perturbative:
$$
F=\Psi^2\log\Psi^2+\text{instantons}
$$
where the instantons come from classical field configurations with a macroscopic value. These have non-vanishing action $S\sim 1/g^2$, so their contribution is $e^{-1/g^2}$ and thus very small.
Anyway, at zero scalar field the classical equations of motion admit non-trivial instanton solutions (cf ref. 1),
$$
A\sim \frac{1}{x^2+\rho^2},\qquad \psi\sim\frac{\gamma}{x^2+\rho^2}
$$
where $\rho$ is the size of the instanton.
For non-zero scalar field, this is no longer a solution to the classical equations of motion, but thanks to supersymmetry one can argue that they still yield the leading contribution to $F$ (essentially, because other contributions vanish!).
So this is a situation where field configurations that do not strictly speaking satisfy the classical equations of motion still give the largest contribution to the path integral. The reason is, other contributions are exactly zero due to the large amount of symmetry provided by $\mathcal N=2$. This is a quite non-generic situation, and you would not expect it to happen in more realistic theories.
References.
- arXiv:hep-th/9602073.