Does the gain medium in a laser need to be replenished? Just what the title states. 
The gain medium in a gas/fluid laser works by shedding stimulant energy. 
My elementary knowledge of physics tells me a photon is mass-less. Ergo, photon emission would continue ad infinitum in the presence of stimulant energy - no need to replenish the medium.
Is this correct? Does the medium eventually need to be replenished? 
 A: A laser's energy is supplied from an outside source, e.g. through optical, electrical or chemical pumping of the gain medium. So the gain medium is not being borne away by its conversion to light energy, if that's what you mean! The energy comes from a separate power supply. However, depending on exactly how you mean your question to be read, one could say that the medium is borne away and must be replenished in an Atom Laser which outputs a coherent beam of atoms from a Bose-Einstein condensate.
Coming back to "light" lasers: you are in principle right: the gain medium atoms / molecules cycle repeatedly exactly back to their beginning states in outputting the laser light and can do so indefinitely. However, at a practical level, no gain medium is immortal. This is especially so for dye lasers: all fluorophores eventually bleach, which means that they have a very specific "mean number of cycles before failure" and thus an exponentially distributed useful lifetime. The transition eventually destroys the fluorophore. It can be very slow (e.g. in an erbium doped fibre amplifier), but it is inevitable. Solid state gain mediums are also eventually degraded by lasing - particularly in high power systems such as Q-switched lasers. Gas lasers leak their gas slowly: I have heard a saying that one should switch an unused HeNe laser on the shelf every six months to help forestall such leaking, but I do not understand how this can help and think that it is probably an experimentalist's urban myth.
A: You're correct that the medium isn't consumed to provide the laser beam energy, so in this sense the medium isn't used up. So for example a ruby laser can operate indefinitely even though it's a chunk of solid and obviously isn't being replenished.
Having said that, there are chemical lasers that do need their medium replacing, but this isn't because the medium is converted into light. It's just because the medium degrades with time.
