To determine whether a nucleus is allowed to decay into another system with the same baryon number, you weigh it. If its mass is more than the mass of the products at the end of the decay, then the decay is allowed. Symmetries which "forbid" the decay really just make it slower — for example, a "third-forbidden" beta decay is faster than a "fourth-forbidden" beta decay.
For example, a neutral carbon-14 atom has a mass of $14.003\ 242$ dalton, while a neutral nitrogen-14 atom has a mass of $14.003\ 074$ dalton. We can look at just the "mass excess," the part of the mass that's different from the mass number $A=14$, and see that there is 0.168 millidalton of mass, or about 150 keV of energy, to be liberated in that decay.
Some energetically-allowed decays may have extremely long lifetimes. For example, potassium-40 may decay to either calcium or argon, via positive or negative beta decay, but the calcium decay is less energetic. This means it is theoretically possible for calcium-40 to "double-beta decay" to argon-40. However, that decay is so slow that it has never been observed.
There is currently no evidence for any decays which change the baryon number (total protons plus neutrons) of a system. The best-studied example would be proton decay where the half-life is no shorter than $10^{34}$ years. This limit was set, roughly, by putting $10^{33}$ protons, as the hydrogen nuclei in water, in a mine full of radiation detectors, and then observing zero proton decays over a decade.