For context, I watched PBS Spacetime's video on virtual particles (link goes to relevant timestamp) where they say that virtual particles aren't mathematically necessary, because the lattice version of nonperturbative QFT doesn't use them, and yet still makes all the same predictions as perturbative QFT. I was satisfied with that, until I had a brief exchange with someone in the comments of this answer where he says that, in most cases, it's impossible to actually do computations in nonperturbative QFT, and, when I asked if this was just due to not having sufficiently efficient algorithms, he said
Note that in particular that even establishing the existence of a non-perturbative Yang-Mills QFT (which is what the standard model / QCD / QFD are) is a millennium problem.
which implies that we don't currently even have a nonperturbative version of the standard model and that it's unclear whether one exists. However, PBS Spacetime is, in my experience, typically a reliable source for high-level explanations, so I wouldn't have expected them to mention nonperturbative QFT as the reason not to think virtual particles are physical if that theory wasn't actually useful for nontrivial calculation. Is it that most physicists think there probably is a nonperturbative version of the standard model and it just hasn't been discovered/created yet?