Surely resonances are not a property of second-order differential equations in general. The night is dark and dreary and even if we assumed the class of smooth non-linear ODEs for a single unknown function, we would struggle to even understand what is meant by your question.
But this is not Mathematics StackExchange, this is Physics StackExchange and I get what you mean. You are asking, whether second-order ODEs representing physical dynamical systems are generally subject to resonant phenomena when some sort of driving term is applied. To this question the answer is yes, at least as far as the system in question is stable, autonomous, the equations of motion (evolution equations) are continuous, and the dissipation is weak in a sense that will be specified later.
Conservative systems
Generally speaking, an autonomous system of a single degree of freedom can be expressed by evolutionary equations of the form
$$\ddot{y} = f(\dot{y},y)$$
where $f(\dot{y},y)$ is some smooth, but generally nonlinear function and dots stand for time derivatives. (The autonomy of the system is expressed by the fact that $f$ is independent of $t$.) Much of the behaviour of this system is characterized by the Poincaré-Bendixson theorem.
The system in question will either be conservative or dissipative. A conservative system means that there is some energy function $E(\dot{y},y)$ such that $\dot{E} = 0$. Such a system can be turned into a first-order equation inverting the energy function as $\dot{y} = \dot{y}(E,y)$. If this system is stable for some set of initial conditions, this means that it stays in some bounded region of $y$ at all times. The theory of dynamical system tells you that this motion is also necessarily periodic (an oscillation) with some frequency $\Omega(E)$ (which does not need to be the same for all amplitudes of oscillation/energies).
Weakly dissipative systems
Now to finish setting the stage, we also briefly mention weak dissipation. Dissipation means, at least for a stable system that stays in some finite range of $y$, that the system evolves to a finite set of limiting points (equilibria, very often just a single one). Weak dissipation means that we can write the equations of motion as a sum of a conservative term and a dissipative term
$$\ddot{y} = f_{\rm c}(\dot{y},y) + f_{\rm d}(\dot{y},y)$$
such that the frequency $\Omega$ of the unperturbed conservative system $\ddot{y} = f_{\rm c}$ decays on some long dissipative time-scale $$\tau_{\rm diss.} = \frac{\Omega}{d\Omega/dt}$$
Now the system is weakly dissipative if $\tau_{\rm diss.}$ is longer than the characteristic period of the motion $\tau_{\rm diss.} \gtrsim 1/\Omega$ or
$$\frac{\Omega^2}{d \Omega/d t} \gtrsim 1$$
Note that this criterion might evaluate differently for different initial conditions, so the dynamical system can be weakly or strongly dissipative only in some parts of the phase space.
The meaning of the weak dissipation criterion is that the system can be understood as a reasonably slowly damped oscillator. In return, there even is a reasonable notion of an oscillation frequency of the system in question. On the other hand, when and if the dissipative time-scale is shorter than the period of the original system, the oscillation gets damped on the scale of less than a period and it is physically meaningless to even talk about a frequency of the system (and thus resonance).
Driving and resonance
Finally, let us talk about driving forces. The driving can be written as
$$\ddot{y} = f_{\rm c} + f_{\rm d} + \epsilon F(\dot{y},y,t)$$
where it is assumed that $\epsilon F/f_{\rm c}$ is small anywhere of interest and that it is periodic with a frequency $\Omega_{\rm drive}$ in $t$. Now the response of the system to this driving force can be captured by perturbation theory and will generally scale with $\epsilon$ in the $\epsilon \to 0$ limit. However, very generally the perturbation theory will diverge in a $\propto \sqrt{\epsilon}$ neighborhood of parts of phase space where $\Omega = \Omega_{\rm drive}$ or even $\Omega = q/r \Omega_{\rm drive}$, where $q,r \in \mathbb{N}$. This is related to the so-called small-divisors problem in analytical mechanics (see also the Kolmogorov-Arnold-Moser theorem). In this neighborhood the system is forced to co-oscillate in some sense with the driving frequency. In the case of dissipative systems, it gets "locked" with the driving frequency for a time $\propto \sqrt{\epsilon}$. This all comes from rather general considerations about the system.
If you would like to learn more about the methods leading to these conclusions, I recommend the 2012 book Multiple scale and singular perturbation methods by Kevorkian & Cole.