This question is a more general (and shorter) version of this previous question of mine. We know that from any quantum-mechanical description of a system, we can go to an equivalent description by transforming the state vector of the system $$ | \tilde{\Psi} \rangle = U |\Psi \rangle $$ and operators (that correspond to observables) by $$ \tilde{O}_n = U O U^{\dagger}. $$ This will yield a new state vector (with a new time evolution). The system is, however, equivalent, in that for any operator, the matrix elements (and especially the expectation values) do not change: $$ \langle \tilde{\Phi} | \tilde{O}|\tilde{\Psi} \rangle = \langle \Phi | O | \Psi \rangle. $$ However, if the state is a solution of the system, then its time evolution is no longer governed by $H$ (or, in the transformed picture, by $\tilde{H}$), but instead by another operator, namely $$ \tilde{H}_N = U H U^{\dagger} + i \hbar (\partial_t U)U^{\dagger} = \tilde{H} + i \hbar (\partial_t U)U^{\dagger}. $$ Meanwhile, the time evolution of the operators also changes. If they were time independent before, they afterwards are $$ \partial_t \tilde{O} = (\partial_t U) U^{\dagger} \tilde{O} + \tilde{O} U\partial_t U^{\dagger}. $$
Which leaves me to ask: When all these frames are equivalent, then what is the right operator that measures "energy"? If I ask for the generator of time translations, then it is not clear anymore which operator that should be. In my example, is $H$ (or $\tilde{H}$) the right operator to look at when one asks, "What can the energy eigenvalues be?" Or is it $\tilde{H}_n$ (or $H_n$)?
In the Schrödinger and in the Heisenberg pictures, there is no ambiguity regarding that question, and the Hamilton operator is the same for both of them. But energy eigenvalues are also calculated in other pictures. Is this a valid procedure?
EDIT: There was a suggestion that this question is a duplicate of this question. I don't think that this is the case: The answer to the suggested question is the starting point of my question. It points out that
if one simultaneously transforms states and observables, then expectation values do not change [... but] the transformed Hamiltonian ceases to be the Hamiltonian of the system since (1) holds in place of $V(t)U_{t}V(t)^{−1}=U_{t}$. (wrong)
This result is already the starting point of my question. What I now want to is: When unitarily equivalent pictures of quantum mechanics (and as the suggested answer pointed out, we can choose any of those pictures, because expectation values do not change) have different Hamiltonians, and if the observable that we call energy is usually the observable that generates time evolution, then which of those many different inequivalent Hamiltonians is the energy of the system?
We usually don't talk about "the energy of the two-level system in the Schrödinger picture" and "the energy of the two-level system in the rotating frame," so the term "energy" seems to refer to a specific choice here. I want to know what choice that is.
At this point (guessing the one comment of Roger Vadim), I believe that the answer to my question is, "What the energy is ultimately depends on how the detector looks like, because this will determine the operator that is measured?"