I would like add to Qmechanic's excellent answer a bit of context from the practical point of view.
Apparently the question arises in classical Quantum mechanics not accounting for relativity. So then we can assume that spinors in 3D transform under the effect of rotations like representations of SU(2) which is the universal covering group of SO(3), the 3D rotation group. The "S" (special) means that the determinant of the unitary matrices of SU(2) is 1.
A bilinear object like $\epsilon_{\alpha\beta}\eta^\alpha \xi^\beta$ with $\eta^\alpha$ and $\xi^\alpha$ as components of non-relativistic spinors in 3D space transforms like
$$\eta'^1 = a\eta^1+b\eta^2\quad\text{and} \quad \eta'^2 = c\eta^1 + d\eta^2$$
if $$U = \left(\begin{array}{cc} a & b\\ c & d\end{array}\right)$$
is a transformation matrix $\in SU(2)$.
If $\xi$ transforms in the same way we find that
$$\epsilon_{\alpha\beta}\eta^\alpha\xi^\beta=\eta'^1\xi'^2 - \eta'^2\xi'^1 = (ad-bc)( \eta^1\xi^2 - \eta^2\xi^1) = \eta^1\xi^2 - \eta^2\xi^1$$
due to the unimodularity of the matrices of SU(2) ($det U=1$).
This means that under SU(2) $$\epsilon_{\alpha\beta}\eta^\alpha\xi^\beta$$ and in particular $$\epsilon_{\alpha\beta}\eta^\alpha\eta^\beta$$ transforms as a scalar.
On the other hand we expect the bilinear
$$\eta^1 \eta^{\ast 1} + \eta^2 \eta^{\ast 2}$$
to be invariant under unitary transformations -- it transforms like a scalar too. We now can identify both bilinear products with each other which leads to the identification of $(\eta^{\ast 1}, \eta^{\ast 2})$ with $(\eta^2, -\eta^1)$.
In other words it means that in 3D spinors and complex-conjugated spinors transform in a very similar way, technically speaking both respresentations are equivalent. This is only true in 3D-space. In Minkowski space, however, the transformation group of spinors is SL(2,C) and the representations of spinors and their complex-conjugated counterpart are no longer equivalent.
It is useful to add that if apart from contravariant spinors $\eta^\alpha$ also covariant spinors $\xi_\alpha$ can be introduced and defined:
$$\eta_1 = \eta^2 \quad \text{and}\quad \eta_2 = -\eta^1$$
We can shortcut this as:
$$\epsilon_{\alpha \beta}\eta^\beta =\eta_\alpha \equiv \eta^{\ast \alpha}$$
and then we can write:
$$\sum_{\alpha=1,2} \eta^\alpha\eta^{\ast \alpha} = \sum_{\alpha=1,2} \eta^\alpha \eta_\alpha$$