No. Notice you'd have a similar problem even in the classical theory. If spacetime is not stationary, you can't really say what is $T_{00}$ in the stress tensor to define what is the energy density, unless you are choosing to define it with respect to some observer, for example. Even in this case, you won't have a global conservation law due to the lack of a timelike Killing field. The fact it is happening due to the indeterminacy in the choice of creation and annihilation operators is pretty much the same problem with extra steps. Note it goes roughly like this:
- particles are modes of positive-define energy;
- there is no preferred notion of energy in a non-stationary spacetime;
- hence, there is no preferred notion of particles in a non-stationary spacetime.