Possible to destroy matter on a "human" scale (i.e. $\mathcal{O}(1m)$) using a proton? A naive calculation suggests that a proton moving in a vacuum at $(1-10^{-38})c$ would have relativistic momentum equal to $\gamma mv \approxeq 2\mathrm{kgms^{-1}}$ if we say $m = 10^{-27}\mathrm{kg}$ (verified using https://keisan.casio.com/calculator). This is obviously a ridiculous amount of momentum for something measuring femtometres across.
However, at this speed, what would happen if, say, a $1$m x $1$m x $0.2$m piece of wood was placed in the direct path of the proton?
Since atomic nuclei are so small compared to the distance between them in the wood, and the protons immense inertia, I would expected it to pass straight through most of the time - but what if it struck a nucleus head-on? Would we see the piece of wood break akin to some sort of bullet impact, or would we see something more like a fission chain reaction as the target nucleus instantly disintegrates into more highly energetic particles?
Further, how would the miniscule de Broglie wavelength of such a particle affect this scenario, if at all?
I realise this is a highly speculative question, but I would like to know if my conjectures seem plausible.
 A: First, I want to advise against direct use of any calculator
for finding the Lorentz factor $\gamma=\frac{1}{\sqrt{1-v^2/c^2}}$,
because in your case this would involve calculating the difference
of two nearly equal numbers ($1$ and $v^2/c^2$).
This is prone to loss of precision.
You can circumvent this issue by doing some algebra first:
$$\gamma = \frac{1}{\sqrt{1-\frac{v^2}{c^2}}}
  = \frac{1}{\sqrt{(1+\frac{v}{c})(1-\frac{v}{c})}}
  = \frac{1}{\sqrt{(2+10^{-38})\cdot 10^{-38}}}
  \approx \frac{1}{\sqrt{2\cdot 10^{-38}}}
  = 7.1\cdot 10^{18}$$
Then the momentum is
$$p = \gamma mv
  \approx \gamma mc
  = 7.1\cdot 10^{18} \cdot 1.7\cdot 10^{-27}\text{ kg}\cdot 3\cdot 10^8\text{ m/s}
  = 3.6\text{ kg}\cdot\text{m/s}$$
which differs significantly from your result ($p=2\text{ kg}\cdot\text{m/s}$).
Let's also calculate the energy:
$$E=\gamma mc^2
  = 7.1\cdot 10^{18} \cdot 1.7\cdot 10^{-27}\text{ kg} \cdot (3\cdot 10^8\text{ m/s})^2
  = 1.1\cdot 10^9\text{ J}$$
With this high energy you are way beyond the realm of
ultra-high-energy cosmic rays ($E > 8\text{ J}$)
and even the Oh-My-God particle ($E=51\text{ J}$).
When such a high-energy particle hits your block of wood, it will most
probably just pass through without causing much ionization of the atoms.
The particle would interact not much with the electrons and nuclei,
just because it flies by very fast and hence there is not enough time
to transfer much momentum and energy to any of these.
In the rare event of a head-on collision with a nucleus,
it would smash the nucleus into pieces and also
produce some particle/antiparticle pairs (see pair production).

(image from Wikipedia - Cosmic rays)
However, the primary high-energy particle still would only loose
a small percentage of its energy in this collison.
So it can do many more such collisions on its way after leaving
the block of wood.
And also the fragments produced by the collision
will later collide with other nuclei on their way
(most probably also after leaving the block of wood).
So you get a cascade of secondary rays.
But the block of wood as a whole would not take any visible damage.
A: First of all it is a little strange to start a naive calculation with the ad hoc speed of $(1-10^{-38})c$. This is obviously very close to speed of light, and the closer you get, the higher the energy of the particle is. Particle physicists usually give the energy of a particle in electronvolts, and if I did not make a mistake, the momentum you gave corresponds to an energy (via $E=pc$, neglecting the mass at such high momentum) of around $10^{27}\mathrm{eV}$. This is even ten million times more energy than the highest energy cosmic rays (also mostly protons) that have been found, while these already have much higher energies than the particles in colliders. There is no known mechanism that could give protons the energy you consider, actually there is not even a known mechanism that explains the highest energy cosmic rays. Cosmic rays hit us all the time. (Although most of them are of 'medium' energy.)
Nevertheless, the process that happens if these particles hit matter, e.g. living materials like wood or tissue is the similar for different energy ranges: There is a certain probability that it will interact with another particle inside the wood/metal/tissue, via the rules of relativistic quantum mechanics, i.e. quantum field theory, and by that the resulting particles produce a lot of secondary and tertiary (and so on) particles, since all the kinetic energy can be converted to mass of other particles. This is similar to the chain reaction you mentioned, but especially in wood I would not know how this could start a 'fission' i.e. nuclear chain reaction. As you mentioned, the high energy leads to a small deBroglie wavelength, which I would think implies that the interaction will happen with individual nucleons, like another proton or a neutron, and not with a whole nucleus. In living tissue these highly kinetic particles can disintegrate molecules and therefore actually destroy cells, which is of course not healthy if it happens in too many cells at once, but as I mentioned, it basically happens all the time. I would not know how a single particle could cause a macroscopic visible 'bullet hole', no matter how high it's energy is, since then it would need to interact with many atoms that are close kind of in sync, and I do not know how that would be possible.
EDIT: I just looked up that the usual beam in the LHC contains all together (it consists of a LOT of particles) around 350 MJ. This is actually roughly the amount of energy you considered for your ONE particle in your question. When the beam is dumped into many tons of metal, the room they shoot it in heats to $800^{\circ}C$. See here for a reference in German. So I think such a ridiculous high energetic particle could lead to so much kinetic energy in the resulting particles that just the heat, which in the end of course comes from the particle interactions, destroys the whole wood block, but this only happens if enough of the resulting particles actually interact within the woodblock.
