This is something I've dug into for a while, and what I am wondering about is the following argument, which I haven't necessarily seen before.
First, we'll take the Wigner's friend variant, because to me, this one makes the strongest argument for the claim in the titular question. In Wigner's friend, for those not familiar with it, we have a quantum system, then a "friend" who will observe that system, then a "Wigner" who observes the "friend": in particular, the quantum system starts in a superposition state, say it's a spinning electron, and its spin state is
$$|\psi\rangle := \frac{1}{\sqrt{2}} \left(|{\uparrow}\rangle + |{\downarrow}\rangle\right)$$
Now here's the first point: we will not make any ontological claims about this superposition. The trick is the next point: the "friend" now measures the rotation axis of the electron and gets and records at least in their head a result, say "$\uparrow$", and now subsequent measurements will return that same result. No problems ... until we look at how "Wigner" would analyze this.
"Wigner" can, just as well, presumably (under some philosophical assumptions like physicalism of the mind) put the "friend" and electron into a giant Schrodinger equation, with hugely complex Hamiltonian operator covering zillions of atoms and a massively complicated initial state, and run it forward. "Wigner", however, will predict then that the combined "friend"-electron system ends up in something that can roughly be considered as
$$|\psi_\mathrm{friend}\rangle := \frac{1}{\sqrt{2}} \left(|\text{I saw a "$\uparrow$"}\rangle\ |{\uparrow}\rangle + |\text{I saw a "$\downarrow$"}\rangle\ |{\downarrow}\rangle\right)$$
and this is then claimed to be problematic in some way. But why is it? If we put Wigner's and friends' experiences on equal footing, then it seems there is no other conclusion you can have but that this simply means that the superposition here actually should be understood as Wigner's knowledge, and Wigner doesn't know which outcome happened.
The question is: why is that a problematic interpretation, beyond potentially taking issue with the philosophical assumptions just mentioned (physicalism of mind, equal footing of different experiences)? Now I am aware that, of course, if we make certain assumptions as to what a superposition is knowledge about, we can run into problems (as any one of a number of theorems that anyone is familiar with the whole topic of quantum foundations would almost surely know by now), but what I am after is a more minimal thesis:
- at bare minimum, quantum states represent knowledge of measurable system parameters,
- according to the "real state of the world", the specific parameter "Did I see a $\uparrow$ or a $\downarrow$?" has a classical outcome before Wigner sees it, despite that Wigner assigned a superposed pure state to his friend.
without any presumption of what the "real state of the world" in (2) is/isn't in the case of general physical systems and/or how that the knowledge in (1) does/doesn't relate to it.
So: what is wrong with this thesis?
Now for what seems to be the objection, and my challenge thereto. Pretty much every no-go result on these things (e.g. Bell, PBR, Frauchiger-Renner, etc.) invariably involves at least one measurement that is analogous to measuring the friend in a basis that itself involves superpositions. And while this seems to just be taken for granted in every presentation I've seen, what my question is is how can we justify this measurement?
Keep in mind what the above $|\psi_\mathrm{friend}\rangle$ is: it is actually the state for/of a huge number of atomic particles, and the states going in on the right are actually just representatives drawn from wide subsets of Hilbert space, corresponding to, say, different ways the friend has cocked their head, different jiggles of their atoms in the course of thermal motion, and so forth. More to the point, the "I saw a $\uparrow$" etc. stuff going into the superposition on the right is a simplified representation of what would, if we are consistent in our application of quantum theory be a very complicated proposition based on the atomic particles.
What result tells us that this measurement is even theoretically possible to make? As it would seem that without it, why can't we just write off the difference between the superposition and a classical uncertainty between the two outcomes above as lying in an unphysical domain or, in a sense, simply being a mathematical artifact that has led theorizers astray?
ADD 1: Someone has mentioned that Wigner's friend could send a signal out of the isolated lab. This won't cut the mustard. The EM field will be ascribed a superposition. That's very basic QED. In effect, we just added another "layer" - the EM field - to Wigner and the friend, between them. When Wigner hears the signal, Wigner will either get one or the other frequency, just as if he opens up the lab.
ADD 2: There is a very simple way to see that anything that would "betray" the superposition in the second case as being something nontrivial would also be seriously physically consequential. Presume it is possible, then do a serial measurement as follows with 3 rounds. First, do what Wigner usually does and open up the lab and ask the friend. The friend has a 50% chance to then be found as
$$|\psi_\mathrm{friend}\ 2\rangle := |\text{I saw a "$\uparrow$"}\rangle\ |{\uparrow}\rangle$$
. Suppose that happens. Now Wigner seals up the lab again and does the questionable part, measuring in the basis
$$\mathcal{B} := \left\{ \frac{1}{\sqrt{2}} \left(|\text{I saw a "$\uparrow$"}\rangle\ |{\uparrow}\rangle + |\text{I saw a "$\downarrow$"}\rangle\ |{\downarrow}\rangle\right), \\ \frac{1}{\sqrt{2}} \left(|\text{I saw a "$\uparrow$"}\rangle\ |{\uparrow}\rangle - |\text{I saw a "$\downarrow$"}\rangle\ |{\downarrow}\rangle\right) \right\}$$
Note this either puts friend in the same state as before or else another with identical probabilities.
Thus Wigner goes and opens the lab again. It is possible, with 50% chance, that what Wigner gets this time is the opposite of what he got in his first measurement, as being what friend saw. General 50% overall chance. In particular, friend's mental state was changed in the meantime, and so too was the state of the quantum particle, and indeed everything else in the lab I just omitted for simplicity from my maths above. Something dramatic had to have happened here. This is not a simple thing - my question is whether it makes even physical sense to ascribe $\mathcal{B}$ as carrying information about a physical property of the system, or if measurement in $\mathcal{B}$ and associated dramatic transformation of reality, is just mathematical fiction/spuriousness.