To elaborate on Qmechanic's answer to show why anticommutation in a bigraded differential algebra is natural, consider a manifold $X$ and its exterior algebra $\Omega(X)$. Suppose that there is a bigrading on $\Omega(X)$ such that $$ \Omega(X)=\bigoplus_{(r,s)\in\mathbb Z^2}\Omega^{r,s}(X), $$ where the sum is a direct sum. Suppose furthermore that when restricted to any pure grade subspace $\Omega^{r,s}(X)$, the exterior derivative goes as $$ d:\Omega^{r,s}(X)\rightarrow\Omega^{r+1,s}(X)\oplus\Omega^{r,s+1}(X). $$
If the bigrading is compatible with the ordinary grading by degree in the sense that each differential form of pure bigrade also has pure "monograde" then this is natural.
We then define the splitting of the exterior derivative as $$ d=d_1 +d_2,\quad d_1=\pi^{r+1,s}\circ d,\quad d_2=\pi^{r,s+1}\circ d,$$ where $$ \pi^{r,s}:\Omega(X)\rightarrow\Omega^{r,s}(X) $$ is the projection - which is well-defined because the bigraded decomposition is a direct sum.
This decomposition is then well-defined on any element by extending linearly. The nilpotency condition $d^2=0$ of the original exterior derivative now gives $$ 0=d^2=\left(d_1+d_2\right)^2=d_1^2+d_2^2+d_1d_2+d_2d_1. $$ Suppose that we applied $d^2$ to an element of pure bigrade $(r,s)$. Then $d_1^2$ maps to $\Omega^{r+2,s}(X)$, $d_2^2$ maps to $\Omega^{r,s+2}(X)$, and both $d_1d_2$ and $d_2d_1$ maps to $\Omega^{r+1,s+1}(X)$. Because of the direct sum decomposition, these subspaces are disjoint and linearly independent, therefore $d_1^2$, $d_2^2$ and $d_1d_2+d_2d_1$ must separately vanish. The first two gives $$ d_1^2=0,\quad d_2^2=0, $$i.e. the derived operators $d_1$ and $d_2$ are also nilpotent differentials, and the third condition gives $$ d_1d_2=-d_2d_1, $$ which shows that $d_1$ and $d_2$ anticommute.