In condensed matter physics, topological quantum field theories provide an effective description of (many, but not all) gapped phases of matter at low energies and long distances. A phase of matter is gapped if it costs a finite amount of energy to create any excitation above the ground state.
Examples of gapped phases of matter that admit a low-energy TQFT description include quantum Hall phases, which are described by Chern-Simons theories, and superconductors with dynamical electromagnetic fields, which are described by $BF$ theories.
Examples of gapped phases that may not have a TQFT description are so-called fracton or gapped non-liquid phases.