"Given statement 1 and 2, no particle can change state at heat death"
Not necessarily. At heat death, particles may still be bouncing around.
https://en.wikipedia.org/wiki/Heat_death_of_the_universe#Current_status
"If the cosmological constant is zero, the universe will approach absolute zero temperature over a very long timescale. However, if the cosmological constant is positive, as appears to be the case in recent observations, the temperature will asymptote to a non-zero positive value, and the universe will approach a state of maximum entropy in which no further work is possible"
When the heat death temperature is above absolute zero, particles are still bouncing off each other and changing position and velocity. It's just that in heat death they are uniformly mixed, at thermodynamic equilibrium, and cannot be used to do any thermodynamic work.
However, you are right that direct observations of heat death are impossible. (Except for Boltzmann brains)
But it would be too restrictive to say, on this basis, that it's not scientific. We can't observe heat death from inside a universe in heat death, but we can look at it "from a distance" (a distance in time) and see the signs. Many billions of years in the future humanity may still be around, and experiencing a universe on an inevitable slide towards heat death - they won't experience heat death itself, because they will be dead first, but they can experience the progress towards it.
We can't observe a nuclear explosion from inside the explosion, either. But this does not mean nuclear explosions are not science. We can observe them from a distance.