Proton crystallography is not typically done because protons have a very shallow penetration depth compared to electrons, photons/x-rays, or neutrons with the same energy. This means that for a proton to penetrate through the same amount of material as another elementary particle (electrons/photons/neutrons), it needs to be accelerated to much higher energy. But, it is that high energy that makes proton-based techniques induce irreversible damage to materials. This damage can be useful in proton therapy, but is undesirable in studying materials otherwise. As an explicit example, the inelastic mean free path of a 300 eV electron in water is about 2 nanometers, but to achieve the same mean free path for a proton you would need it to be accelerated to over 1,000,000 eV.
Nonetheless, protons are plentiful (compared to neutrons) and don't deposit a lot of energy through electromagnetic radiation, so they have found use in imaging heavy bulk materials like lead as discussed in the other answer by JEB. However, it should be stressed here that to do proton radiography you need to accelerate protons to very high energies (about a gigavolt) so you can't make a benchtop proton imager like you could with electron or x-ray imagers. It's also worth mentioning that protons deposit more kinetic energy in the final length of their travel at the so-called "Bragg peak" (unrelated to crystallography). This behavior can be compared to electrons which deposit much more through electromagnetic radiation at the beginning of their penetration.
However, while proton microscopes are uncommon, there are Helium ion microscopes commercially available that can achieve incredible spatial resolution down to 0.5 nanometers (about 2-3 carbon atoms wide). The reason Helium is used is because it tends not to stick or bond to materials because Helium is an inert noble gas, while protons (a.k.a. ionized Hydrogen) readily bond to most materials and change their physical, chemical, and biological properties. The shallow penetration depth compared to electrons is actually an advantage here, because it gives a lot of surface contrast and better resolution.
Compared to electrons, the higher mass of Helium atoms (or protons for that matter) allows them to be focused to even smaller spot sizes (smaller de Broglie wavelength) with even less penetration (high surface contrast and minimal spread) due to the better momentum transfer to nuclei compared to light electrons. There are a number of other advantages as well (see this paper) such as minimal sample damage, higher contrast without the need of metal coating, and less susceptibility to charging. Practically, the higher mass of Helium atoms also means only electrostatic lenses are needed, which is useful since magnetic lenses are heavier and have larger aberrations.
One exciting use of these Helium ion microscopes is studying biological materials that are difficult for electron microscopes. Most biological objects are insulating/non-metallic so traditional scanning electron microscopes require metallic coating. In addition, electron beams readily generate x-rays which damages sensitive biological structures, but heavier protons and Helium ions produce much less x-rays so they cause less damage. In my opinion, Helium ion microscopes will be very useful for a lot of different fields going forward. Nonetheless, these instruments are quite specialized of course.
Zeiss sells such a Helium ion microscope, take a look at the instrument below.
Using a Helium ion microscope, you can take some very nice images of the Arabidopsis thaliana plant taken from this paper as also shown below.