Disclaimer The question below is based on a vague knowledge, and hence, statements can be potentially wrong or misleading.
An important quantity in Cosmology is the density fluctuation of matter quantified in terms of the ratio $$\frac{\delta\rho(\textbf{x})}{\bar{\rho}}=\frac{\rho(\textbf{x})-\bar{\rho}}{\bar\rho}\tag{1}$$ where $\bar{\rho}$ is the average density. If I understand it correct, the information of CMB anisotropies enables us to predict the density fluctuations at the time of recombination.
Question $1$ Is it meaningful to talk about density fluctuations $\frac{\delta\rho(\textbf{x})}{\bar{\rho}}$ for the present universe?
Question $2$ If yes, how can it be measured and what is its present value, and can it be related to its primordial value?