Is there a simple generally accepted explanation for single photon interference?
Does each photon interact with or see both slits?
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If you are talking about the double slit experiment, then it is a misconception that it is done with just a single photon. It is done with a single photon shot at the screen one at a time, repeated many times. The interference pattern is built by many photons.
Now there are two mentioning of interference on this site, usually with photons and the double slit experiment:
the interference pattern itself, that is built up by many photons, shot one at a time. The reason for the pattern in this case is that the photons' are emitted by the same experimental setup laser (or other lightsource), and their wavefunctions entanglement is described mostly the same way as per QM, thus the same characteristics for the photons shot after each other will make them entangle with the slits and the whole system (photons and slits) will cause the photons' landing positions on the screen to show the same pattern, some bright areas, where the photons are landing that created constructive interference and a dark areas where you see no photons land because those created destructive interference
the interference of the single photon that is shot at a time, meaning that the photon's partial waves travel through both slits and then after the slits these partial waves interfere with each other. Now this interference can be constructive, meaning a bright spot on the screen, meaning that a real photon reached the screen and interacted with the screens atoms. This interference can be desctructive too, where the partial waves of the photon interfere so that they basically annihilate the photon as a real particle itself, which would have landed on the (theoretically) dark area. But it does not land on the screen at all, and does not interact with the screen's atoms at all, because it was annihilated on the fly. Particles can be annihilated by their antiparticles, and the photon happens to be its own antiparticle.