Yes, when electromotiv force (emf) otherwise known as potenital difference or voltage exists between unequal amounts of electrical charge an electric field then exists which attracts charged particles of opposite polarity. When these charged particles move in this direction, they are reacting to the electromotiv force.
The motion of charged particles in reaction to electromotiv force is known as electrical current. The relationship between emf and current is defined by Ohms law
R = V/I where I is current measured in amperes, V is emf or voltage measured in volts, and R is resistance measured in ohms. When electrical current flows through a conductor, the molecules within the medium are heated. The greater the Resistance to current flow, the more heat is caused. You can say the molecules are getting more average kinetic energy by reacting to the electrical current flow.
Also, there is reaction when electrical current or voltage is varied. In electromagnetics, the term reactance is used to describe either inductance or capacitance. When electrical current is changed the reactance is inductance. When electrical voltage is changed the reactance is capacitance. These are defined by Faraday's laws and Maxwell's equations.