above: From Scientific American, Juan Collar, a professor in physics at the University of Chicago, with a prototype of the world’s smallest neutrino detector used to observe for the first time an elusive interaction known as coherent elastic neutrino nucleus scattering. Credit: Jean Lachat / University of Chicago
I'd like to add to this excellent, concise answer describing the Gargamelle experiment (also see CERN) first results reported in 1973; the first observation of elastic scattering due to the "weak force". From sixty-symbols:
The discovery involved the search from two types of events: one involving the interaction of a neutrino with an electron in the liquid; in the other the neutrino scattered from a hadron (proton or neutron). The signature of a neutral current event was an isolated vertex from which only hadrons were produced. By July 1973 they had confirmed as many as 166 hadronic events, and one electron event. In both cases, the neutrino enters invisibly, interacts and then moves on, again invisibly. On 3 September the collaboration published two papers on these events in the same issue of Physics Letters.
The article further states the size of the detector:
Gargamelle was 4.8 metres long and 2 metres in diameter. It weighed 1000 tonnes and held nearly 12 cubic metres of heavy-liquid freon (CF3Br). (emphasis added)
Since I originally posted the question, some new and notable results have been published. From the Scientific American article titled Ever-Elusive Neutrinos Spotted Bouncing Off Nuclei for the First Time; A new technology for detecting neutrinos represents a “monumental” advance for science
:
That rarity has made life miserable for physicists, who resort to building huge underground detector tanks for a chance at catching the odd neutrino. But in a study published today in Science, researchers working at Oak Ridge National Laboratory (ORNL) detected never-before-seen neutrino interactions using a detector the size of a fire extinguisher. [...] The new experimental collaboration, known as COHERENT, instead looks for a phenomenon called CEvNS (pronounced “sevens”), or coherent elastic neutrino-nucleus scattering. (emphasis added)
From the recently published and open access! article in Science Observation of coherent elastic neutrino-nucleus scattering (D. Akimov et al. Science 03 Aug 2017:eaao0990, DOI: 10.1126/science.aao0990):
[...] Soon thereafter it was suggested that this mechanism should also
lead to coherent interactions between neutrinos and all nucleons
present in an atomic nucleus (2). This possibility
would exist only as long as the momentum exchanged remained
significantly smaller than the inverse of the nuclear
size (Fig. 1A), effectively restricting the process to neutrino energies below a few tens of MeV. The enhancement to the
probability of interaction (scattering cross-section) would
however be very large when compared to interactions with
isolated nucleons, approximately scaling with the square of
the number of neutrons in the nucleus (2, 3). For heavy nuclei
and sufficiently intense neutrino sources, this can lead
to a dramatic reduction in detector mass, down to a few
kilograms.
To simplify, low energy neutrinos (tens of MeV) produced by the decay of pions, themselves a biproduct of GeV proton-nucleus collisions are detected by a block of (very pure, carefully formulated) salt as flashes of light with several specific characteristics. The radius of a nucleus is roughly 1.3 femtometers times $A^{1/3}$, so a Cesium or Iodine nucleus is going to be about 13 fm. For strong coherent scattering from all nucleons, the wavelength should be at least twice that. The corresponding momentum should be below 46 MeV/c, and conveniently the decay energy of $\pi^{+,-} \rightarrow \mu^{+,-}$ is about 34 MeV, producing a continuum of neutrino energies below that value. The pion decays produced a prompt neutrino signal, while the muon decay produced a delayed secondary source of neutrinos at higher energies. Both can be seen in the data.
One of the major challenges of the experiment was to shield the detector from the extremely strong neutron flux from the spallation source, and to distinguish the extremely low energy elastic neutrino-nucleus scattering from all of the other scintillation signals produced in the detector
The results are summarized in the abstract:
The coherent elastic scattering of neutrinos off nuclei has eluded detection for four decades, even though its predicted cross-section is the largest by far of all low-energy neutrino couplings. This mode of interaction provides new opportunities to study neutrino properties, and leads to a miniaturization of detector size, with potential technological applications. We observe this process at a 6.7-sigma confidence level, using a low-background, 14.6-kg CsI[Na] scintillator exposed to the neutrino emissions from the Spallation Neutron Source (SNS) at Oak Ridge National Laboratory. Characteristic signatures in energy and time, predicted by the Standard Model for this process, are observed in high signal-to-background conditions. Improved constraints on non-standard neutrino interactions with quarks are derived from this initial dataset. (emphasis added)