Negative Energy States
Following on from Cham's answer, in Quantum Mechanics the negative matter will still have energy $E = \hbar \nu$ since $E \rightarrow - E$ and $\hbar \rightarrow - \hbar$, meaning the de Broglie wavelength is positive. The Uncertainty principle is
$$(\Delta x)^2 (\Delta P_x)^2 \geq \hbar^2/4$$
Whereas another relation is
$$(\Delta x) (-\Delta P_x) \geq -\hbar/2$$
The Heisenberg equation is also invariant, mass becomes negative in the Schrodinger equation and since energy-momentum operators are invariant. Hence
$$-E=\frac{p^2}{-2m}+U(r)$$
Corresponding to
$$i \hbar \frac{\partial \psi}{\partial t}=\frac{\hbar^2}{2m}\nabla^2 \psi -U(r) \psi$$
Here only $U \rightarrow -U$. The Klein-Gordon equations and Dirac equations are also invariant.
Negative matter in Inflationary Cosmology
The Standard model of Inflationary Cosmology has problems. They relate to expansion, antimatter, flatness etc. The Schwarzschild metric of negative matter should be
$$ds^2 = \left(1+\frac{2m}{r} \right)dt^2 - \frac{dr^2}{1-(2m/r)}-r^2 (d \theta^2 + \sin^2 d \phi^2)$$
Einstein and Rosen investigated the particle problem in GR, proposing a new variable, namely $u^2=r+2m$ or, $u= \pm \sqrt{r+2m}$ gives two corresponding sheets to $u >0$ and $u < 0$ are then joined by the Einstein-Rosen bridge to $r=-2m$ (or $u=0$) for which $g_{\mu \nu}=0$.