I have learned from high school and college that, for a conductor of uniform cross section, its DC resistance is inversely proportional to the cross-sectional area. I have no doubt that this holds true in practice, for the purpose of everyday electrical appliances and electronics.
But is there a certain scale of things at which this relationship breaks down? For example, if I put $10^{-20}$ Volts across, does it make any difference whether the cross section is $1\,\text{km}^2$ or $100\,\text{km}^2$?