If we consider a spin-$\frac12$ particle at rest in the absence of any potentials, we can use the Pauli spin operators and an associated basis to describe the observable.
Let's arbitrarily choose the $Z$ basis and consider the particle to initially be in state $\newcommand{\k}[1]{\left|\;#1\;\right\rangle}$ $\k{\downarrow}$.
If we then move into an accelerating reference frame, do we require a new spin operator? Secondly, what is the spin state of the particle in this new reference frame?
To make this somewhat more intuitive, this question arose from considering a particle in free fall in a uniform gravitational field. Does the spin state change depending on whether we measure the particle in the laboratory frame or the particle own frame of reference?
EDIT:
The particle and its measurement apparatus are at rest in a laboratory. They are technically in an accelerating reference frame subject to gravitational forces. The spin is measured and found to be in the $\k{\downarrow}$ eigenstate. If we then release both the particle and the apparatus, they will be in an inertial (freely falling) frame. Is there a way to quantify the state of the particle now? Will it still be in the $\k{\downarrow}$ eigenstate or do the eigenstate have to be redefined altogether?