The unit vector $\hat{r}_{21}$ shows that the force is parallel to the line joing the charges. It could be otherwise unless space itself has some built-in directional property. . . This can be predicted by logical arguments from symmetry. - Berkely Physics Course Vol. 2 by Edward M Purcell.
Now, the question seems to be totally nonsense; but I do actually want to know why is the force acting parallel to the line joining charges. Or what led to assume(??) that the force is acting in that direction; it could be anywhere acting. How can I use symmetry to prove this? Plz help.