In the simplest form the saddle point method is used to approximate integrals of the form
$$I \equiv \int_{-\infty}^{\infty} dx\,e^{-f(x)}.$$
The idea is that the negative exponential function is so rapidly decreasing — $\;e^{-10}$ is $10000$ times smaller than $e^{-1}$ — that we only need to look at the contribution from where $f(x)$ is at its minimum. Lets say $f(x)$ is at its minimum at $x_0$. Then we could approximate $f(x)$ the first terms of its Taylor expansion.
$$f(x) \approx f(x_0) + \frac{1}{2}(x- x_0)^2 f''(x_0) +\cdots.$$
There is no linear term because $x_0$ is a minimum. This may be a terrible approximation to $f(x)$ when $x$ is far from $x_0$, but if $f(x)$ is significantly bigger than its minimal value in this region then it doesn't really matter, since the contribution to the integral will be negligible either way. Anyway plugging this into our integral
$$I \approx \int_{-\infty}^{+\infty} dx\, e^{-f(x_0) - \frac{1}{2}(x-x_0)^2 f''(x_0)}= e^{-f(x_0)}\int_{-\infty}^{\infty} dx\, e^{-\frac{1}{2}(x-x_0)^2 f''(x_0)}.$$
The gaussian integral can be evaluated to give you
$$I = e^{-f(x_0)}\sqrt{\frac{2\pi}{f''(x_0)}}.$$
So where does this come up in physics? Probably the first example is Stirling's approximation. In statistical mechanics we are always counting configurations of things so we get all sorts of expressions involving $N!$ where $N$ is some tremendously huge number like $10^{23}$. Doing analaytical manipulation with factorials is no fun, so it would be nice if there was some more tractable expression. Well we can use the fact that:
$$N! =\int_0^\infty dx\, e^{-x}x^N = \int_0^\infty dx \exp(-x +N\ln x).$$
So now you can apply the saddle point approximation with $f(x) = x -N\ln x$. You can work out the result yourself. You should also convince yourself that in this case the approximation really does become better and better as $N\rightarrow \infty$. (Also you have to change the lower bound of the integral from $0$ to $-\infty$.)
There are lots of other examples, but I don't know your background so it's hard to say what will be a useful reference. The WKB approximation can be thought of as a saddle point approximation. A common example is in partition function/ path integrals where we want to calculate
$$\mathcal{Z} = \int d\phi_i \exp(-\beta F[\phi_i]),$$
where the $\phi_i$ are some local variables and $F[\cdot]$ is the free energy functional. We do the same as before but now with multiple variables. Again we can find the set $\{\phi_i^{(0)}\}$ that minimizes $F$ and then expand
$$F[\phi_i] = F[\phi_i^{(0)}] +\frac{1}{2}\sum_{ij}(\phi_i -\phi_i^{(0)})(\phi_j -\phi_j^{(0)})\frac{\partial^2F}{\partial\phi_i\partial\phi_j}.$$
This gives you the ground state contribution, times a Gaussian (free) theory which you can handle by the usual means. Following the earlier remarks we expect this to be good in the limit $\beta\rightarrow \infty$, although your mileage may vary.