Imagine a small ball of gravitating dust particles initially at rest at the center of a large volume $V$.
Following John Baez, Einstein's field equations say (in units of $c=8 \pi G=1$):
$$\frac{\ddot{V}}{V} = - \frac{1}{2} (\rho + 3 p)$$
Now traditionally dust particles have a pressure $p=0$.
However the dust particles have a mutual gravitational attraction for each other.
Could this mutual attraction be described within the framework of GR by assigning a negative pressure $p$ to the ball of dust particles?
Another way of looking at it is to say that the ball of dust particles has a certain amount of negative gravitational self-energy which counteracts some of the gravitational effects of its positive rest mass energy.
Apparently the concept of gravitational energy in GR is complex so maybe negative pressure is a better way to think about it.