The Navier-Stokes system for incompressible fluid says $$ \begin{aligned} \dot{\mathbf{u}} + (\mathbf{u}\cdot\nabla)\mathbf{u}-\nu\Delta\mathbf{u}+\nabla{p} &= 0,\\ \nabla\cdot\mathbf{u}&=0. \end{aligned} $$ The non-slip boundary condition for the velocity $\mathbf{u}$ says $\mathbf{u}|_{\partial\Omega}=0.$ But the pressure boundary condition is unclear. Most references I found use Neumann boundary condition which is $\nabla{p}\cdot\mathbf{n}=0$ on $\partial\Omega$ ($\mathbf{n}$ is normal vector of $\partial\Omega$). As consequence, $p$ can be determined up to an arbitrary additive constant! Does this make any sense in physics? How can I determine the constant?
There is also an initial value condition for $p$. We can add an arbitrary function $q(t)$ satisfying $q(0)=0$ to $p(\mathbf{x},t).$ That is, if $p(\mathbf{x},t)$ is a solution, so is $p(\mathbf{x},t)+q(t).$