In QED, the fine structure constant $\alpha$ runs upwards in the UV, with a loop calculation (involving a geometric series of the vacuum polarisation diagram) indicating a divergence in $\alpha$ at $\sim 10^{286}\,\text{eV}$. It is often claimed (see, for instance, Schwartz, QFT and the Standard Model, section 21.2) that this means QED is an incomplete theory at high energies, or that it is not predictive at these energies, and that some UV completion is required.
However, QCD is another theory with a Landau pole (in the IR this time), at $\sim100\,\text{MeV}$. Neverthless, QCD is a theory valid down to arbitrarily low energies; it is merely non-perturbative in this regime. My understanding is that the Landau pole is an artefact of extrapolating a perturbative calculation of the coupling strength $\alpha_s$ into the non-perturbative regime. In fact, there is no divergence in $\alpha_s$, although explicitly calculating it is impossible (or perhaps not even meaningful) with current tools and understanding.
Therefore, whilst perturbation theory clearly breaks down in QED at very high energies, is it not possible that QED is a perfectly legitimate and consistent theory up to arbitrarily high energies, in much the same way that QCD is at low energies? Is the QED Landau pole really there?
Said another way, is there really any link between "the point at which perturbation theory breaks down" and "the point at which the theory stops being predictive"? Perhaps these are linked when we're working with an EFT with infinitely many terms whose coefficients are unconstrained, but if we postulate the QED Lagrangian as fundamental, is it not, at least in principle, predictive up to arbitrarily high energies?