Practically, for a macroscopic body such as a chunk of metal, the charge on that body is the difference between the number of electrons and protons in the body. It is hard to knock a proton out (can be done, though), but for conductors we can push and pull electrons out by supplying a bit of energy (back to that in a moment). However, instead of saying the a chunk of metal has one more electron than the number of protons, we say that the object has $-1.6\,10^{-19}$ Coulombs of charge. Similarly, if we have one fewer electrons, the object has $+1.6\,10^{-19}$ of charge.
Why do we care? Phenomenologically, it is because electrons and protons attract each other while two of the same type repulse each other. We can talk about underlying theories as to why, but those theories are trying to explain the physical phenomenon that we see if we pass a free electron near a free proton.
So, if we have an excess of electrons in one object and a dearth in the other, the excess electrons in the first attracts the excess protons in the other and the objects will get pulled together (e.g. capacitor plates attract each other). For two charge neutral objects, the bulk electrons in one object still get attracted to the protons in the other, but they are equally repulsed by the bulk electrons in the other and there is no net force. (Note that is is possible to generate some force between two neutral objects if the electrons aren't uniformly distributed across the object because there is distance dependence on the force).
Hopefully that helps with one part of your question. The second part was how do you charge an object. Because each and every electron in a neutral object is attracted to the protons in the object, if we were to pull and electron off the object, it will have a force pulling it back to the (now) charged object. We have to do some work and supply some energy to get that electron off. There are a lot of ways to do this, but the most common is probably a battery. A battery uses chemical processes to pull electrons from its positive terminal to its negative terminal. So the positive terminal is positively charged and the negative is negatively charged. Another way is to hit an object with high enough energy light such that the electron pops off the surface. That is how the Millikan oil drop experiment worked. Pop electrons off the drops of oil and see how the drop moves when put between two metal plates where one plate has excess electrons and the other has a dearth of electrons. The drop will move.