Any valid long English text encoded as ascii or whatever you specify in advance found early in pi can be your possible message. You can limit acceptable messages so the odds are you will not find one. You might find a message in French and throw it out, and thus fail to discover something valid. Or you might accept it, and maybe discover nonsense because you have violated the confirmation bias limits. Or an English message might be valid or invalid. Or there might be nothing to discover. You can arrange so that if you find something, the odds are it isn't chance.
If you do find something, the process doesn't tell you if it is unusual luck, great wisdom, a great lie, or something else.
However science can take a position on "we know there are these things which would cause exactly this" or at least "we may not know the cause but we have repeatedly seen this happen occasionally". So science certainly can say that something is not a miracle, only a low-probability event. More than that, it must, because if you attribute anything at all, ever, to divine intervention then you destroy any possibility to investigate a physical source. And that is directly opposed to rational thinking. We have historical proof of why this is wrong.
Your problem there is confirmation bias. If you have a sufficiently large random sample (such as, hypothetically, the digits of pi), then any encoding you care to pick (maybe ASCII) will eventually find a string of digits which produce the message "I'm God and I'm a black woman. Fix the Sistine Chapel ceiling.". Just for an example. It's equally likely as the encoding producing "zadfafhtyuweljhbgjkfyfqemgeghrhdf", because that's how probability works. The risk for miracle hunting is that you find something because you're looking for something without knowing exactly what.
My point is that you have to say beforehand what message you're looking for. If you can't do that, then you can't calculate odds, because that would be asking "what's the probability of finding something I've already found?" to which the answer is "exactly 1, because you've already found it". But if you can predict it then by your definition it's not a miracle, so you'rea bit stuck there.