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David Z
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The problem is this:

"Consider an electron confined in a region of nuclear dimensions (about 5 fm). Find its minimum possible kinetic energy in MeV. Treat this problem as one-dimensional, and use the relativistic relation between E and p."

Consider an electron confined in a region of nuclear dimensions (about 5 fm). Find its minimum possible kinetic energy in MeV. Treat this problem as one-dimensional, and use the relativistic relation between E and p.

From Heisenberg's uncertainty relation for position and momentum $\Delta x \Delta p\geq\frac{ℏ}{2}$, $\Delta pc= \frac{ℏc}{2\Delta x}=39.4MeV$$\Delta pc= \frac{ℏc}{2\Delta x}=39.4\text{ MeV}$ where $2\Delta x=5fm$$2\Delta x=5\text{ fm}$ is the width of the region. Plugging this into the relativistic energy-momentum relation $E^2=(mc^2)^2+(pc)^2$, $E=39.4MeV$$E=39.4\text{ MeV}$ which is the correct answer.

However, in my book there is also an equation for the zero-point energy which is defined as the lowest possible kinetic energy for a quantum particle confined in a region (one-dimensional) of width $a$ and is given by $\langle K \rangle= \frac{ℏ^2}{2ma^2}$ and the answer I get here is about $1.52 GeV$$1.52\text{ GeV}$.

Why are/should these answers be so different?

Also the questions says "The large value you will find is a strong argument against the presence of electrons inside nuclei, since no known mechanism could contain an electron with this much energy."

How is this argument made exactly?

The problem is this:

"Consider an electron confined in a region of nuclear dimensions (about 5 fm). Find its minimum possible kinetic energy in MeV. Treat this problem as one-dimensional, and use the relativistic relation between E and p."

From Heisenberg's uncertainty relation for position and momentum $\Delta x \Delta p\geq\frac{ℏ}{2}$, $\Delta pc= \frac{ℏc}{2\Delta x}=39.4MeV$ where $2\Delta x=5fm$ is the width of the region. Plugging this into the relativistic energy-momentum relation $E^2=(mc^2)^2+(pc)^2$, $E=39.4MeV$ which is the correct answer.

However, in my book there is also an equation for the zero-point energy which is defined as the lowest possible kinetic energy for a quantum particle confined in a region (one-dimensional) of width $a$ and is given by $\langle K \rangle= \frac{ℏ^2}{2ma^2}$ and the answer I get here is about $1.52 GeV$.

Why are/should these answers be so different?

Also the questions says "The large value you will find is a strong argument against the presence of electrons inside nuclei, since no known mechanism could contain an electron with this much energy."

How is this argument made exactly?

The problem is this:

Consider an electron confined in a region of nuclear dimensions (about 5 fm). Find its minimum possible kinetic energy in MeV. Treat this problem as one-dimensional, and use the relativistic relation between E and p.

From Heisenberg's uncertainty relation for position and momentum $\Delta x \Delta p\geq\frac{ℏ}{2}$, $\Delta pc= \frac{ℏc}{2\Delta x}=39.4\text{ MeV}$ where $2\Delta x=5\text{ fm}$ is the width of the region. Plugging this into the relativistic energy-momentum relation $E^2=(mc^2)^2+(pc)^2$, $E=39.4\text{ MeV}$ which is the correct answer.

However, in my book there is also an equation for the zero-point energy which is defined as the lowest possible kinetic energy for a quantum particle confined in a region (one-dimensional) of width $a$ and is given by $\langle K \rangle= \frac{ℏ^2}{2ma^2}$ and the answer I get here is about $1.52\text{ GeV}$.

Why are/should these answers be so different?

Also the questions says "The large value you will find is a strong argument against the presence of electrons inside nuclei, since no known mechanism could contain an electron with this much energy."

How is this argument made exactly?

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Minimum possible Kinetic Energy of a confined electron

The problem is this:

"Consider an electron confined in a region of nuclear dimensions (about 5 fm). Find its minimum possible kinetic energy in MeV. Treat this problem as one-dimensional, and use the relativistic relation between E and p."

From Heisenberg's uncertainty relation for position and momentum $\Delta x \Delta p\geq\frac{ℏ}{2}$, $\Delta pc= \frac{ℏc}{2\Delta x}=39.4MeV$ where $2\Delta x=5fm$ is the width of the region. Plugging this into the relativistic energy-momentum relation $E^2=(mc^2)^2+(pc)^2$, $E=39.4MeV$ which is the correct answer.

However, in my book there is also an equation for the zero-point energy which is defined as the lowest possible kinetic energy for a quantum particle confined in a region (one-dimensional) of width $a$ and is given by $\langle K \rangle= \frac{ℏ^2}{2ma^2}$ and the answer I get here is about $1.52 GeV$.

Why are/should these answers be so different?

Also the questions says "The large value you will find is a strong argument against the presence of electrons inside nuclei, since no known mechanism could contain an electron with this much energy."

How is this argument made exactly?