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I've been working with LAMMPS, NAMD and ESPResSoMD and I can tell you ESPResSoMD is the best package for simulating coarse-grained models. It has two versions: Tcl and python based interface ( the python one has not been released officially, but you can get a development version of it).

Post Made Community Wiki by Mohammadreza Niknam Hamidabad