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I propose this : As long as the detailed balance is respected, the system can be studied with equilibrium thermodynamic. Therefore we can write the free energy of the solution, for exemple $F=A \log(A) + B \log(B) + S \log(S) + \chi_{A S} A S + \chi_{B S} B S + \chi_{A B} A B$ ($S$ the solvent, $\chi$ the interaction parameters), plug the equilibrium ...