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OP here, this is my best guess. I'm interested if anyone has a better answer. I use the covalent radii listed on Wikipedia. As an approximation, I assume all carbon are $sp^3$ hybridized, and I interpolate oxygen's radius. In picometers: Hydrogen radius = 32 Oxygen radius = 60 Carbon radius = 76 Therefore, using $V = 4/3 \pi r^3$, $V_{Hydrogen} = 4/3 ...

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