Very nice statement from wiki:
When three or more unrelated parameters are measured, their total MSE can be reduced by using a combined estimator such as the James–Stein estimator; whereas when each parameter is estimated separately, the least squares (LS) estimator is admissible.
So I wonder if it offers any new interpretation for distinction between micro(lot of quantum phenomenons) and macro(where everything seems to be defined "more precisely" when "looking at the object as a whole") world.