I'm wondering why the weak interaction only affects left-handed particles (and right-handed antiparticles).
Before someone says "because thats just the way nature is" :-), let me explain what I find needs an explanation:
In the limit of massless fermions, chirality (handedness) becomes helicity $(\vec S \cdot \hat p)$. Now, helicity is a property of the state of motion of an object in space. It is pretty unobvious to me how the internal symmetry $SU(2) \times U(1)$ would "know" about it, and be able to distinguish the two different helicity states of motion.
On a more technical level, IIRC, left and right handed spinors are distinguished by their transformation properties under certain space-time transformations, and are defined independent of any internal symmetry. If we want to get the observed V-A / parity violating behavior, we have to plug in a factor of $(1 - \gamma^5)$ explicitly into the Lagrangian.
Is there any reason this has to be like this? Why is there no force coupling only to right handed particles? Why is there no $(1 + \gamma^5)$ term? Maybe it exists at a more fundamental level, but this symmetry is broken?